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Hydroxypropyl Betadex

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  • Time of issue:2021-08-19
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(Summary description)

Hydroxypropyl Betadex

(Summary description)

  • Categories:News
  • Author:
  • Origin:
  • Time of issue:2021-08-1912
  • Views:
Information

CAS NO.: 128446-35-5

Quality standards: usp40, ep9.0, bp2015, cp2015

Level: oral and injection

Package specification: 10kg / barrel, 20kg / barrel

Application: medicine, food, cosmetics

Uses: solubilizer, embedding agent, stabilizer, flavor masking agent

Product introduction

Hydroxypropyl beta cyclodextrin- β- cyclodextrinHP- β- CD, hpbcd) yes β- A hydrophilic derivative formed by condensation of CD with 1,2-propylene oxide. β- Hydroxyl groups at different positions of Cd were randomly substituted by hydroxypropyl to form 2-HP- β- CD2,3-HP- β- CD26-HP- β- CD and 2, 3, 6-hp- β- CD equivalent.

 

Application

1. In the field of medicine, hydroxypropyl- β- Cyclodextrin can solve the problem of water solubility of insoluble or insoluble drugs (including plant extracts); Through molecular embedding,to improve the biological solubility of drugs, to control the release rate of drugs,to improve the bio-availability of drugs, enhance the stability of drugs and reduce the toxic and side effects of drugs.

2. In the field of daily chemical industry, it is used as stabilizer, emulsifier and deodorizer in cosmetic raw materials, which can reduce the irritations to skin and mucous membrane caused by organic molecules in cosmetic, enhance the stability of active ingredients and prevent the volatilization and oxidation of nutrients; Increase the water solubility of insoluble flavor and spices; Keep the fragrance slow-release and lasting; The inclusion can also improve the stability and long-term effect of nutritional molecules, cover up or correct the bad smell and taste of nutritional molecules, and improve the production process and product quality.

 

Certificate of analysis

Clarity of Solution

The solution is clear

Conform

ConductivityμS·cm-1

200

13.88

Betadex%

1.5

0.084

Propylene Glycol%

2.5

0.0064

Any other single impurity%

0.25

Absent

Total impurities excluding betadex and propylene glycol%

1

Absent

Loss on Drying%

10.0

4.1

The Total Aerobic Microbial Countcfu/g

10²

20

The Total Combined Molds and Yeasts countcfu/g

10²

<10

Escherichia Coli

Absent

Absent

Bacterial EndotoxinsEU/g

<10

<10

MS

0.40~1.50

0.83

DS7*MS

2.80~10.50

5.80

Propyleneoxide%

0.0001

0.000041

PH

5.0~7.5

6.3

 

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