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Features and applications of Betadex Sulfobutyl Ether Sodium

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  • Time of issue:2021-08-16
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(Summary description)

Features and applications of Betadex Sulfobutyl Ether Sodium

(Summary description)

  • Categories:News
  • Author:
  • Origin:
  • Time of issue:2021-08-1644
  • Views:
Information

Betadex Sulfobutyl Ether Sodium  is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.

 

Betadex Sulfobutyl Ether Sodium has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.

 

Product performance:

1. Solubility:

Neutral, positive and negative APIs can be effectively combined with betadex sulfobutyl ether sodium to increase the solubility of the compound by 10 to 25,000 times.

2. Facilitate the drug

Betadex Sulfobutyl Ether Sodium has a good biocompatibility and can be administered by injection, oral, ocular, nasal, topical and inhalation.

3. Good security

In general, it can be quickly and completely removed from the kidneys after administration. In vitro experiments and in vivo acute, subacute and chronic toxicity studies provide safe data and approval for use with pharmaceutical preparations.

4. Good stability

The interaction with sulfobutyricotriacodextrin provides a beneficial protective environment for the drug substance in its lipophilic chamber, while the hydrophilic surface provides excellent water solubility to provide solubility and stability.

 

If you're looking for the high-quality Betadex Sulfobutyl Ether Sodium, our company will be your best choice. We're one of the leading manufacturers and supplier with rich experience and wide expertise. Please be rest assured to buy the products from our factory.

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